Roy Hodgson is set to make 11 changes to his team for Sunderland's trip to Anfield on Saturday.
The boss told his pre-match press conference that none of those who took to the field at the beginning of our Carling Cup defeat to Northampton would start against Steve Bruce's outfit.
"None of the players who are playing on Saturday played on Wednesday night," said Hodgson.
"We had a very bad result on Wednesday night but it should not affect the 11 players who are going to start the game on Saturday because they weren't part of the game.
"We rested the whole team that played against Man Utd, plus Dirk Kuyt. That had unfortunate consequences but at least it means they're all fresh and ready for tomorrow's game."
Asked whether Kuyt could return from a shoulder injury earlier than expected against the Black Cats, Hodgson added: "Kuyt is the only one we have a slight reservation about but we'll see if he makes it. Therefore the only serious injury situation is Fabio Aurelio."
Hodgson was also asked about Daniel Agger's comments to Danish TV, which were taken out of context and reported in English newspapers.
He responded: "This happens a lot. A player is not in the team, he does an interview on his national television, people then take his answers and put different questions to them.
"The boy is very, very upset because he hasn't said these things but it's another nice little headline after the defeat to Manchester United."
Reporters wanted to know if the manager would now speak with Agger about the situation.
"I don't give players mass media training," he said. "I would give mass media training to young players but Agger has played many games for Liverpool and Denmark - I wouldn't want to pull him aside and say, 'Be careful what you say." He already understands those things.
"You are going to get caught out."
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