For Saturday I would play the 1st half full strength available and change it in the half time.
NB: Team no longer available
This may well be the starting lineup. I wonder how they would do the 2nd half if Matip is not available (he is at least present at training), because then you only have one center back (Phillips) and one full back (Moreno) in reserve. I wonder if the U23s have staarted training yet and if so, they might pull a couple of those in for the 2nd half back line. I doubt they want anyone to play more than 45 minutes at this point of preseason.
At midfield they could use Pedro Chirivella, Gini and Curtis Jones if they wanted - and then up front any three of Solanke, Sturridge, Ings, Wilson, Ojo, Kent, Camacho. Or Lallana could play midfield the first half Milner the 2nd, and one of those six forwards up front in the first half. Lots of options.
I'm eager to see what Jürgen does, although I am reminded that a lot of these preseason matches are little more than training exercises.